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Porcine Protein Phosphatase 1 Regulatory Subunit 14B (PPP1R14B) ELISA Kit-Sandwich

Cat. No.EK12F657

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Porcine Protein Phosphatase 1 Regulatory Subunit 14B (PPP1R14B) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine Protein Phosphatase 1 Regulatory Subunit 14B (PPP1R14B) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Porcine PPP1R14B.
Target Species Swine
Species Reactivity Swine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Protein Phosphatase 1 Regulatory Subunit 14B (PPP1R14B), also known as Swiprosin-1, is a protein encoded by the PPP1R14B gene in pigs. It is a poorly defined member of the protein phosphatase 1 regulatory subunits. Aberrant upregulation of PPP1R14B has been observed in triple-negative breast cancer (TNBC) tissues and is associated with poor prognosis. The PPP1R14B protein is capable of inhibiting PP1 and several PP1 holoenzymes. It localizes to the juxtamembrane of smooth muscle cells and is involved in the regulation of the trailing edge of migrating cells and modulates the retraction of endothelial and epithelial cells.

Target/Biomarker Porcine PPP1R14B
Target Synonym Protein phosphatase 1 regulatory subunit 14B; Phosphatase holoenzyme inhibitor 1; PHI-1; Ubiquitous PKC-potentiated PP1 inhibitor; PPP1R14B; PHI1
Gene ID 397205
UniProt ID Q8MIK9

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Deng, M. et al. PPP1R14B Is a Prognostic and Immunological Biomarker in Pan-Cancer. Frontiers in genetics. 2021, 12: 763561.
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