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Mouse Toll Like Receptor 9 (TLR9) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Toll Like Receptor 9 (TLR9) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TLR9 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Toll-like receptor 9 (TLR9) plays a crucial role in both innate and adaptive immunity. Toll-like receptors (TLRs) are responsible for mediating the host's immune response to pathogens by identifying specific molecular patterns associated with microorganisms. TLR9, specifically, is a nucleotide-sensing receptor activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. In mice, TLR9 activates the innate immune system by recognizing CpG DNA, thereby regulating a range of immune responses and disease processes. Its functions extend beyond defending against infections; it also plays a part in regulating autoimmune diseases, inflammatory conditions, and maintaining intestinal microbial balance. Research indicates that mice lacking TLR9 exhibit a significant reduction in the production of anti-double-stranded DNA (dsDNA) and anti-histone antibodies, though the production of anti-Sm antibodies remains unaffected.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.