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Mouse Orosomucoid 2 (ORM2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Orosomucoid 2 (ORM2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ORM2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Orosomucoid-2 acts as a transport protein in the bloodstream, binding various ligands within its beta-barrel domain. It appears to play a role in modulating immune system activity during the acute-phase response. In mice, ORM2 has a range of complex functions, including regulating neuroinflammation, microglial activation, bone metabolism, and immune regulation in adipose tissue. ORM2 exhibits different effects across various disease models. In the rheumatoid arthritis (RA) mouse model, ORM2 may directly enhance the inflammatory response. Additionally, ORM2 has been linked to bone metabolic diseases; during bone remodeling, it contributes by inhibiting osteoblast differentiation and promoting osteoclast differentiation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Kim, Ki-Myo et al. "The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation." Experimental & molecular medicine vol. 56,4 (2024): 890-903.