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Mouse Sulfatase 2 (SULF2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Sulfatase 2 (SULF2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SULF2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Extracellular sulfatase Sulf-2 possesses arylsulfatase activity along with a highly specific endoglucosamine-6-sulfatase activity. It effectively removes sulfate from the C-6 position of glucosamine in particular subregions of intact heparin. Sulf2 is essential for embryonic development, particularly for the nervous system's development. Although mice lacking Sulf2 experience mild weight loss and developmental delays, they generally do not exhibit significant neuroanatomical abnormalities or behavioral defects. However, Sulf2-deficient mice show differences in certain neurobehavioral tests, such as grip strength assessments and cage activity monitoring, performing worse likely due to reduced neurite outgrowth.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Holst, Charles R et al. "Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival." PloS one vol. 2,6 e575. 27 Jun. 2007.