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Mouse D-Dimer (D2D) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse D-Dimer (D2D) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse D2D in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mouse models, D-Dimer is chiefly involved in thrombosis and fibrinolysis, inflammatory response, disease diagnosis and prognosis evaluation, and the regulation of the fibrinolytic system. As a fibrin degradation product, D-Dimer reflects the fibrinolytic system's activity. Its concentration serves as a crucial indicator for assessing thrombosis and fibrinolysis states in these models. The generation of D-Dimer is intricately linked to the fibrinolytic system's activity, where the absence of plasminogen activators (like PAI-1) results in heightened fibrinolytic activity and elevated D-Dimer levels. Additionally, D-Dimer may participate in other pathophysiological processes; for instance, in a lung injury model, increased D-Dimer levels might be associated with enhanced fibrinolytic system activation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wolthuis, Esther K et al. "Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury." Critical care research and practice vol. 2011 (2011): 217896.