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Mouse Sirtuin 3 (SIRT3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Sirtuin 3 (SIRT3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SIRT3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
NAD-dependent protein deacetylase sirtuin-3, also known as Sirtuin 3, is an enzyme that relies on NAD to modulate the acetylation state of mitochondrial proteins by deacetylating specific lysine residues. Sirt3 plays a crucial role in preserving mitochondrial function by regulating protein acetylation levels. It can deacetylate important mitochondrial enzymes like acetyl-CoA synthetase 2 (ACLY) and long-chain acyl-CoA dehydrogenase (LCAD), influencing fatty acid oxidation and energy metabolism. In mice lacking Sirt3, there is hyperacetylation of mitochondrial proteins, resulting in impaired fatty acid oxidation and the onset of metabolic syndrome-related diseases.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.