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Bovine Thiopurine S-Methyltransferase (TPMT) ELISA Kit-Sandwich

Cat. No.EK11F554

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Thiopurine S-Methyltransferase (TPMT) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Thiopurine S-Methyltransferase (TPMT) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine TPMT.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Thiopurine S-Methyltransferase is encoded by the TPMT gene in cattle. It is an S-adenosyl methionine-dependent methyltransferase. TPMT plays a crucial role in metabolizing thiopurine compounds. It transfers a methyl group from S-adenosyl-L-methionine (SAM) to thiopurines, resulting in their inactivation. The byproduct of this reaction is S-adenosyl-L-homocysteine. TPMT is best known for its role in metabolizing drugs such as azathioprine, 6-mercaptopurine, and 6-thioguanine.

Target/Biomarker Bovine TPMT
Target Synonym thiopurine S-methyltransferase; thiopurine methyltransferase
Gene ID 511644
UniProt ID Q17QQ2

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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