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Mouse Sjogren Syndrome Antigen B (SSB) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Sjogren Syndrome Antigen B (SSB) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SSB in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mouse models, the function of Sjogren's syndrome antigen B (SSB/La) is primarily associated with autoimmune reactions and the abnormal activation of B cells. SSB/La serves as a significant autoantigen, with its antibodies (anti-SSB/La antibodies) commonly detected in human Sjogren's syndrome patients, where they are closely linked to disease severity. Studies in mouse models have demonstrated that B cells play a crucial role in the development of Sjogren's syndrome-like diseases (SjS-like disease). For instance, the NOD.B10-H2b mouse model exhibits pathological features similar to human Sjogren's syndrome, such as lymphocytic infiltration of the salivary glands, secretory dysfunction, and the production of autoantibodies.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.