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Mouse Protein Phosphatase 3, Regulatory Subunit 1 (PPP3R1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Protein Phosphatase 3, Regulatory Subunit 1 (PPP3R1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PPP3R1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Protein Phosphatase 3, Regulatory Subunit 1 (PPP3R1), also known as CnB1, acts as a regulatory subunit of calcineurin, a calcium-dependent, calmodulin-activated protein phosphatase, providing calcium sensitivity. In mice, PPP3R1 plays a critical role in the calcineurin signaling pathway, which is crucial for heart development, calcium signaling, and cellular aging. Research has indicated that mice with a targeted knockout of the PPP3R1 gene (csCnB1-/-) suffer from severe cardiomyopathy, characterized by abnormal function of ventricular systole and diastole, without structural defects. These mice die shortly after birth, underscoring the essential role of PPP3R1 in maintaining normal cardiac function and calcium signaling.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.