Mouse Procollagen II C-Terminal Propeptide (PIICP) ELISA Kit-Competitive

In mice, Procollagen II C-Terminal Propeptide (PIICP) is crucial for the assembly, degradation, and maintenance of collagen tissue structure stability. As part of the type II collagen precursor molecule, PIICP's primary function is intimately connected to collagen formation and tissue structure stability. Inside cells, PIICP contributes to the assembly of collagen molecules, facilitating the formation of triple helical structures by maintaining the connection of single chains. Externally, PIICP is degraded by specific proteases, such as ADAMTS-3, within the extracellular matrix, initiating the formation of collagen fibers. This degradation process is vital for normal tissue development and repair. During mouse development, type II collagen and its precursor molecules, including PIICP, are instrumental in the formation of bones and cartilage.