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Mouse Polymeric Immunoglobulin Receptor (PIGR) ELISA Kit-Sandwich

Cat. No.EK5F674

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Polymeric Immunoglobulin Receptor (PIGR) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PIGR in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Polymeric Immunoglobulin Receptor (PIGR).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The polymeric immunoglobulin receptor facilitates the selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. It binds to these immunoglobulins at the basolateral surface of epithelial cells, and the resulting complex is transported across the cell to be secreted at the apical surface. During this process, a cleavage event occurs, separating the extracellular portion, known as the secretory component, from the transmembrane segment. In mice, pIgR is essential for the mucosal immune system, mediating the transmembrane transport of SIgA and SIgM to protect mucosa from pathogens and regulate the host immune response.

Target/Biomarker Mouse PIGR
Target Synonym SC; Secretory Component; Hepatocellular carcinoma-associated protein TB6
Gene ID 18703
UniProt ID O70570

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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