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Mouse Interleukin 17F (IL17F) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interleukin 17F (IL17F) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IL17F in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interleukin 17F is an effector cytokine involved in both innate and adaptive immune systems, playing a key role in antimicrobial defense and maintaining tissue integrity. It signals through the IL17RA-IL17RC heterodimeric receptor complex, prompting interactions between the IL17RA and IL17RC chains and the TRAF3IP2 adapter via SEFIR domains. Produced by Th17 cells, IL-17F works alongside IL-17A to regulate inflammatory responses. Mouse model studies have shown IL-17F's pathogenic role in colitis by attracting neutrophils. In the model of HSV-1-induced ocular infection, IL-17F expression was noted, potentially promoting corneal angiogenesis. Research indicates that the absence of IL-17F can reduce angiogenesis and thereby alleviate disease progression.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.