Mouse Vascular Endothelial Growth Factor 121 (VEGF121) ELISA Kit-Sandwich

VEGF121, a key member of the VEGF family, plays a crucial role in promoting angiogenesis. Research indicates that VEGF121 stimulates the proliferation and migration of endothelial cells by interacting with its receptors Flt-1 and KDR, thus enhancing angiogenesis. In mice, vascular endothelial growth factor 121 (VEGF121) is primarily involved in angiogenesis, anti-angiogenesis, and regulatory effects related to various diseases. While VEGF121 is known for promoting angiogenesis, it can also exhibit anti-angiogenic effects under certain pathological conditions. For instance, in a mouse model of preeclampsia, the injection of VEGF121 has been shown to lower blood pressure and improve renal function, likely due to its regulatory influence on placental angiogenesis and endothelial function.