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Mouse Dickkopf Related Protein 3 (DKK3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Dickkopf Related Protein 3 (DKK3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DKK3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Dickkopf-related protein 3 (Dkk3) inhibits canonical Wnt signaling by preventing the interaction of LRP5/6 with Wnt and by forming a ternary complex with the transmembrane protein KREMEN, which promotes internalization of LRP5/6. DKK proteins are crucial in vertebrate development, where they locally inhibit Wnt-regulated processes such as antero-posterior axial patterning, limb development, somitogenesis, and eye formation. Research demonstrates that overexpression of Dkk3 can reduce cardiac damage and fibrosis following myocardial infarction, while Dkk3 knockout mice experience more severe cardiac dysfunction and ventricular remodeling.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.