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Mouse Amyloid Precursor Protein (APP) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Amyloid Precursor Protein (APP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse APP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Amyloid-beta precursor protein acts as a cell surface receptor with essential physiological roles on the surface of neurons, including promoting neurite growth, neuronal adhesion, and axonogenesis. The interaction between APP molecules on adjacent cells facilitates synaptogenesis. It also plays a role in cell mobility and transcription regulation via protein-protein interactions. APP can enhance transcription activation by binding to APBB1-KAT5 and inhibit Notch signaling through its interaction with Numb. Functional studies in mice have demonstrated APP's significant involvement in Alzheimer's disease pathogenesis, encompassing Aβ generation, toxic aggregation, neuronal dysfunction, and neuroprotection.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.