Mouse 5-Hydroxytryptamine Receptor 1A (5HTR1A) ELISA Kit-Sandwich

The 5-hydroxytryptamine receptor 1A is a G-protein coupled receptor that interacts with 5-hydroxytryptamine (serotonin). It also acts as a receptor for a variety of drugs and psychoactive substances. Mice lacking the Htr1a gene exhibit a notable increase in anxiety-related behaviors. This receptor is broadly distributed in different brain regions, such as the prefrontal cortex, hippocampus, and dorsal nucleus. It plays a crucial role in influencing emotions and behaviors by modulating the release and signaling of serotonin (5-HT). For instance, activating Htr1a can help alleviate anxiety, whereas inhibiting it could heighten anxiety and aggressive behavior. During the development of mice, the expression pattern of Htr1a in specific brain areas is vital for the development and maturation of neurons.