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Equine Indoxyl Sulfate (IS) ELISA Kit-Sandwich

Cat. No.EK2F350

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Equine Indoxyl Sulfate (IS) ELISA Kit-Sandwich is designed for the quantitative determination of Equine Indoxyl Sulfate (IS) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Equine IS.
Target Species Equine
Species Reactivity Equine
Detection Range 31.26-2000 ng/mL
Sensitivity 17.1 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 210 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Indoxyl sulphate (IS, also known as 3-indoxyl sulphate and 3-indoxyl sulphuric acid, is a metabolite of dietary L-tryptophan that acts as a cardiotoxin and uremic toxin. It is derived from dietary protein, specifically from the metabolism of tryptophan. Indoxyl sulfate is a pathogenic factor for sarcopenia in chronic kidney disease. While it is well-known as a nephrovascular toxin, its effects on central nervous system (CNS) cells are still being studied.

Target/Biomarker Equine IS
Target Synonym IS; indoxyl sulfate; serum indoxyl sulfate

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Sato, E. et al. Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease. Scientific reports. 2016, 6: 36618.
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