Mouse Salusin Alpha (SALa) ELISA Kit-Competitive

Salusin Alpha exhibits several physiological functions in mice, including cardiovascular protection, metabolic regulation, and anti-inflammatory effects. It provides notable protection to the cardiovascular system; studies have demonstrated that Salusin Alpha can shield the myocardium from ischemic injury by mitigating endoplasmic reticulum (ER) stress. Specifically, it prevents cardiomyocyte apoptosis and necrosis by downregulating proteins associated with ER stress, such as GRP78, active Caspase-12, and CHOP, while upregulating Bcl-2 expression. Furthermore, Salusin Alpha has been shown to reduce the progression of coronary atherosclerotic lesions. In models of non-alcoholic fatty liver disease (NAFLD), Salusin Alpha improves lipid metabolism disorders by modulating the LKB1/AMPK signaling pathway, inhibiting hepatic steatosis, and lowering plasma triglyceride (TG) levels.