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Chicken Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) ELISA Kit-Sandwich

Cat. No.EK9F270

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Chicken PCSK9 ELISA Kit-Sandwich is designed for the quantitative determination of Chicken proprotein convertase subtilisin/kexin type 9 (PCSK9) in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Chicken PCSK9.
Target Species Chicken
Species Reactivity Chicken
Detection Range 0.2-10 ng/mL
Sensitivity 0.03 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 180 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Proprotein convertase subtilisin/Kexin type 9, also known as PCSK9, is an enzyme encoded by the PCSK9 gene. This protein plays a major regulatory role in cholesterol homeostasis. In an HFD-induced obese chicken model, correlation analysis indicated that 5-hydroxyisourate, alpha-linolenic acid, bovinic acid, linoleic acid, and trans-2-octenoic acid might be transported from gut to liver, and thereby up-regulate the expression of ACSS2, PCSK9, and CYP2C18 and down-regulate one or more genes of CDS1, ST8SIA6, LOC415787, MOGAT1, PLIN1, LOC423719, and EDN2 in the liver to enhance the lipogenesis of chicken.

Target/Biomarker Chicken PCSK9
Target Synonym proprotein convertase subtilisin/kexin type 9; proprotein convertase subtilisin/kexin type 9
Gene ID 424664
UniProt ID A0A8V0ZRU9

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Chen, C. et al. Integrated metabolomic and transcriptomic analysis reveals potential gut-liver crosstalks in the lipogenesis of chicken. Animals. 2023, 13: 1659.
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