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Bovine Presenilin-2 (PSEN2) ELISA Kit-Sandwich

Name: Bovine Presenilin-2 (PSEN2) ELISA Kit-Sandwich
SKU: EK11F646
Rating: 5 (1 reviews)

Cat. No.EK11F646

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Presenilin-2 (PSEN2) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Presenilin-2 (PSEN2) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine PSEN2.

Target Species Bovine

Species Reactivity Bovine

Detection Range 31.2-2000 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Presenilin-2 is encoded by the PSEN2 gene in cattle. It is one of the three proteins that are dominantly mutated in familial Alzheimer's disease (FAD). PSEN2 plays a critical role in Alzheimer's disease pathogenesis. PSEN2 forms the catalytic core of the γ-secretase complex-a function shared with its homolog presenilin-1 (PSEN1). It is a transmembrane presenilin protein. The cow PSEN2 has a length of 449 amino acids.

Target/Biomarker Bovine PSEN2

Target Synonym presenilin 2; presenilin-2; PS-2; presenilin 2 (Alzheimer disease 4)

Gene ID 282010

UniProt ID Q9XT96

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Madsen, L. B. et al. Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain. BMC Neuroscience. 2007, 8: 72.