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Native Bovine Liver Keratin 8 (KRT8)

Name: Native Bovine Liver Keratin 8 (KRT8)
SKU: AP2F135
Rating: 5 (1 reviews)

Cat. No.AP2F135

Product TypeAnimal Proteins

Size

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Product Overview

BioVenic's Native Bovine Liver Keratin 8 (KRT8) is a native protein derived from Bovine Liver.

Specifications

Type Native Protein

Species Bovine

Source Liver

Purity >95% (SDS-PAGE)

Predicted Molecular Weight 52 kDa

Physical State Lyophilized

Formulation 30 mM Tris/HCI pH 8, 9M Urea, 2 mM DTT, 2 mM EDTA, 10 mM Methylammonium Chloride.

Target Information

Keratin, Type II Cytoskeletal 8 is also known as keratin-8. Type II keratin belongs to a group of intermediate filaments found in the cytoplasm of various epithelial cells throughout the body. Research has shown that conditional knockout of Krt8 (keratin 8) within nucleus pulposus aggravates load-induced intervertebral disc degeneration in vivo, and overexpression of Krt8 endows NP cells greater resistance to overloading-induced apoptosis and degeneration in vitro.

Protein Bovine Keratin 8 (KRT8)

Protein Synonym keratin 8; KRT2-8; keratin, type II cytoskeletal 8; CK-8; K8; KERA; cytokeratin 8; cytokeratin-A; type-II keratin Kb8

Gene ID 281269

UniProt ID P05786

Shipping and Storage

Store at 2-8°C (lyophilized) or at -20°C (reconstituted). Avoid freeze and thaw cycles.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.