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Recombinant Chicken Acetylcholinesterase (ACHE)
Product Overview
BioVenic's Recombinant Chicken Acetylcholinesterase (ACHE) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 83.0 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Acetylcholinesterase (ACHE) is a crucial enzyme involved in the hydrolysis of acetylcholine (ACh), a neurotransmitter that plays a significant role in synaptic transmission. ACHE is primarily found at postsynaptic neuromuscular junctions, particularly in muscles and nerves, where it terminates neuronal signaling by breaking down ACh into acetic acid and choline. This process is essential for preventing excessive muscle contraction and maintaining normal nerve function. In addition to its role in the nervous system, ACHE has been implicated in non-neuronal functions, such as skeletal development and immune regulation. Abnormal expression or inhibition of ACHE can lead to various disorders, including muscle paralysis and neurodegenerative diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.