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Bovine Gamma-Aminobutyric Acid Receptor Subunit Alpha-3 (GABRA3) ELISA Kit-Sandwich

Cat. No.EK11F530

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Gamma-Aminobutyric Acid Receptor Subunit Alpha-3 (GABRA3) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Gamma-Aminobutyric Acid Receptor Subunit Alpha-3 (GABRA3) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine GABRA3.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Gamma-Aminobutyric Acid Receptor Subunit Alpha-3 is encoded by the GABRA3 gene in cattle. It is an alpha subunit that forms part of the GABA-A receptors. These receptors are ligand-gated chloride channels and are activated by the major inhibitory neurotransmitter in the mammalian brain, GABA. Research has shown that Gabra3 activates the AKT pathway to promote breast cancer cell migration, invasion and metastasis.

Target/Biomarker Bovine GABRA3
Target Synonym gamma-aminobutyric acid type A receptor subunit alpha3; gamma-aminobutyric acid receptor subunit alpha-3; GABA(A) receptor subunit alpha-3; gamma-aminobutyric acid (GABA) A receptor, alpha 3; gamma-aminobutyric acid type A receptor alpha3 subunit
Gene ID 282237
UniProt ID P10064

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Gumireddy, K. et al. The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis. Nature communications. 2016, 7: 10715.
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