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Canine Diablo IAP-binding mitochondrial protein (Diablo) ELISA Kit-Sandwich

Name: Canine Diablo IAP-binding mitochondrial protein (Diablo) ELISA Kit-Sandwich
SKU: EK10F612
Rating: 5 (1 reviews)

Cat. No.EK10F612

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Canine DIABLO ELISA Kit-Sandwich is designed for the quantitative determination of Canine DIABLO in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Canine DIABLO.

Target Species Canine

Species Reactivity Canine

Detection Range 32-2000 pg/mL

Sensitivity 6.25 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 180 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Diablo IAP-binding mitochondrial protein is encoded by the DIABLO gene in dogs. During apoptosis, the caspase inhibitory properties of IAPs can be neutralized by IAP antagonists, such as the mitochondrial proteins Smac/DIABLO, Omi/HtrA2, and GSPT1/eRF3 that bind to IAP proteins in a manner that displaces caspases.

Target/Biomarker Canine DIABLO

Target Synonym diablo IAP-binding mitochondrial protein; DBO; diablo homolog mitochondrial; diablo homolog; mitochondrial diablo-like protein

Gene ID 477463

UniProt ID A0A8C0Z6Z3

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Wilkinson, J. C. et al. VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation. The Journal of biological chemistry. 2004, 279: 51091-51099.