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Mouse Fibulin 2 (FBLN2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Fibulin 2 (FBLN2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FBLN2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Fibulin-2 exhibits calcium-dependent binding to fibronectin and other ligands, potentially serving as an adapter that facilitates interactions between FBN1 and ELN. In mice, Fibulin-2 plays a wide range of roles, including contributions to cardiac development, elastic fiber formation, tissue repair, immune regulation, and cancer progression. While Fbln2-deficient mice show normal elastic fiber assembly during cardiac development, they display significantly reduced TGF-β signaling in angiotensin II (Ang II)-induced myocardial fibrosis. This attenuation of TGF-β signaling leads to a decrease in myocardial fibrosis and ventricular dysfunction.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.