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Recombinant Staphylococcus aureus Enterotoxin Type B (entB), C-His
Product Overview
BioVenic's Recombinant Staphylococcus aureus Enterotoxin Type B (entB), C-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 32.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
SEB is a potent superantigen secreted by Staphylococcus aureus. It bypasses normal antigen processing by binding directly to MHC class II molecules and specific T-cell receptor (TCR) Vβ regions. This interaction triggers a massive release of pro-inflammatory cytokines (cytokine storm), leading to food poisoning and potentially fatal toxic shock syndrome. Structurally, it consists of two major domains and is highly resistant to heat and digestive proteases, making it a significant clinical and biodefense concern.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.