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Recombinant Streptococcus agalactiae CYK3/IgdE3 Protein, N-GST and C-His
Product Overview
BioVenic's Recombinant Streptococcus agalactiae CYK3/IgdE3 Protein, N-GST and C-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 76.7 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
In Streptococcus agalactiae (Group B Streptococcus), CYK3/IgdE3 is a specialized cysteine protease belonging to the IgdE family (Immunoglobulin-degrading enzymes). It specifically targets and cleaves human immunoglobulin G (IgG), particularly the IgG3 subclass, at the hinge region. By neutralizing antibody-mediated functions such as opsonophagocytosis and complement activation, IgdE3 serves as a potent immune evasion factor. Its role in subverting the host's adaptive immune response makes it a significant target for therapeutic inhibitors and a candidate for multi-component GBS vaccines.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.