Recombinant Rabbit Transthyretin (Ttr), N-His

Rabbit Transthyretin (Ttr) is a highly conserved homotetrameric protein that primarily functions as a carrier for thyroxine (T4) and retinol (vitamin A) in the body. It forms complexes with retinol-binding protein (RBP) to facilitate the transport of retinol in the bloodstream. In rabbits, Ttr is synthesized in the liver and choroid plexus, similar to humans, and plays a role in maintaining thyroid hormone and retinol homeostasis. Additionally, Ttr has been implicated in neuroprotection, particularly in the central nervous system, where it may help reduce the toxicity of amyloid-beta (Aβ) oligomers and promote neuronal survival. This protein also has potential roles in the retina, where it is involved in the visual cycle and may support retinal function. Overall, Ttr is essential for nutrient transport and has emerging roles in neuroprotection and cellular health.