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Recombinant Equine C-C Motif Chemokine 5 (CCL5)
Product Overview
BioVenic's Recombinant Equine C-C Motif Chemokine 5 (CCL5) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 11.6 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Equine C-C motif chemokine 5, also known as equine CCL5, is a chemokine that plays a significant role in the immune system, particularly in the recruitment and activation of leukocytes during inflammatory responses. It acts as a ligand for chemokine receptors CCR1, CCR3, and CCR5, directing the migration of monocytes/macrophages and T cells. CCL5 is involved in the modulation of the inflammatory response in several pathological conditions and has been implicated in the pathogenesis of inflammatory disorders such as multiple sclerosis, HIV dementia, and rheumatoid arthritis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.