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Recombinant Porcine Matrix Metalloproteinase 13 (MMP13), N-His
Product Overview
BioVenic's Recombinant Porcine Matrix Metalloproteinase 13 (MMP13), N-His is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 20.1 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
Matrix metallopeptidase 13, also known as collagenase 3, is encoded by the MMP13 gene in pigs. Research found that the presence of IL-1α, IL-1RA, IL-2, IL-4, IL-6, and IL-10 and MMP-2, MMP-3, MMP-12, and MMP-13 in the synovial fluid was associated with better cartilage outcomes in a porcine model.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH 7.4) to a concentration of 0.1-1.0 mg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Donnenfield, J. I. et al. Predicting severity of cartilage damage in a post-traumatic porcine model: Synovial fluid and gait in a support vector machine. PloS one. 2022, 17: e0268198.