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Recombinant Canine Interleukin 18 Receptor 1 (IL18R1), C-His
Product Overview
BioVenic's Recombinant Canine Interleukin 18 Receptor 1 (IL18R1), C-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 37.3 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine Interleukin 18 Receptor 1 (IL18R1) is a key cytokine receptor involved in immune regulation and inflammation in dogs. It binds to IL-18, a pro-inflammatory cytokine, and activates signaling pathways like NF-kappa-B, which promotes the production of inflammatory mediators. IL18R1 is expressed in various immune cells, including natural killer (NK) cells and T cells, and plays a role in their activation and function. In canine models, IL18R1 has been found to be differentially expressed in inflammatory mammary cancer, suggesting its potential as a biomarker. It also supports immune responses against infections and cancer by enhancing the activity of immune cells.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.