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Recombinant Mouse Parathyroid Hormone-Related Protein (Pthlh), N-His
Product Overview
BioVenic's Recombinant Mouse Parathyroid Hormone-Related Protein (Pthlh), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 17.4 kDa. The purity is> 97%.
Specifications
Target Information
In mice, Parathyroid Hormone-Related Protein (Pthlh) is a multifunctional protein involved in various physiological and pathological processes. Pthlh is crucial for skeletal development, where it regulates endochondral ossification and chondrocyte differentiation. It plays a key role in epithelial-mesenchymal interactions during mammary gland and tooth development. Pthlh is also implicated in cancer progression, particularly in promoting tumor growth and metastasis. Additionally, Pthlh is involved in preimplantation embryonic development, influencing blastocyst formation and the expression of pluripotency-related genes. In the context of disease, Pthlh has been associated with conditions such as hypercalcemia of malignancy and brachydactyly. Overall, Pthlh is a versatile molecule with diverse applications in research, particularly in understanding development, cancer, and metabolic disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.