Recombinant Mouse Prolactin (Prl), N-His-GST

In mice, Prolactin (Prl) is a polypeptide hormone that plays a central role in various physiological processes. Prl is primarily known for its role in promoting milk production and the development of mammary glands. It stimulates the growth of mammary alveoli and the synthesis of milk components such as lactose, casein, and lipids. Prl also regulates the menstrual cycle and is involved in immune modulation and hematopoiesis. Additionally, Prl has been implicated in cancer progression, particularly in breast cancer, where it can promote tumor growth and metastasis. Prl signaling occurs through specific receptors (Prl-R), which belong to the type I transmembrane receptor family. The activation of these receptors leads to the activation of intracellular signaling molecules, including Jak2 kinase and Stat transcription factors. Overall, Prl is a multifunctional hormone with diverse applications in research, particularly in understanding reproductive biology, immune regulation, and cancer biology.