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Recombinant Chicken Ephrin Type-A Receptor 3 (EPHA3)
Product Overview
BioVenic's Recombinant Chicken Ephrin Type-A Receptor 3 (EPHA3) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 109.9 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Ephrin Type-A Receptor 3 (EPHA3) is a receptor tyrosine kinase that binds to ephrin-A ligands, mediating contact-dependent bidirectional signaling. It plays a crucial role in regulating cell adhesion, migration, and axon guidance during embryonic development. EPHA3 is highly expressed in the developing nervous system, particularly in the retina and brain, where it influences the formation of neural circuits. In chickens, EPHA3 is also implicated in the regulation of cell proliferation and differentiation in various tissues. Abnormal expression of EPHA3 has been associated with several diseases, including cancer, where it can influence tumor progression and metastasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.