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Recombinant Mouse Programmed Cell Death 1 Ligand 2 (PDCDLG2), C-Fc

Cat. No.AP2C774

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Programmed Cell Death 1 Ligand 2 (PDCDLG2), C-Fc is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 27.8 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 27.8 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse Programmed Cell Death 1 Ligand 2, or PDCDLG2, is a ligand related to programmed cell death, involved in immune response regulation. In mouse models, PDCDLG2 is used to study immune checkpoint regulation and immunotherapy potential. As an immune checkpoint molecule, PDCDLG2 interacts with its receptor to modulate the activity of immune cells, preventing excessive immune activation and maintaining self-tolerance. In cancer immunotherapy, the blockade of immune checkpoints has shown promising results in enhancing antitumor immune responses. Research on PDCDLG2 focuses on understanding how its interaction with immune cells can be harnessed to develop new immunotherapeutic agents. By targeting PDCDLG2, it may be possible to either enhance immune responses in cancer patients or suppress pathological immune reactions in autoimmune and inflammatory diseases.

Protein Mouse Programmed Cell Death 1 Ligand 2 (PDCDLG2)
Protein Synonym PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD273
Gene ID 58205
UniProt ID Q9WUL5

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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