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Recombinant Mouse Annexin A2 (Anxa2), N-His

Cat. No.AP4C868

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Annexin A2 (Anxa2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 40.4 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 97%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 40.4 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Annexin A2 (Anxa2) is a multifunctional calcium-dependent phospholipid-binding protein involved in various biological processes. It forms a heterotetrameric complex with S100A10, which is crucial for its functions. Anxa2 is involved in membrane repair, redox regulation, and signal transduction. It supports the fusion of exocytic vesicles and interacts with ion channels and GPCRs. In cancer, Anxa2 modulates tumor cell resistance to apoptosis by interacting with pathways related to ROS, autophagy, and the DNA damage response. Anxa2 also plays a role in proliferative vitreoretinopathy, where its deficiency in mice leads to resistance to the development of this condition.

Protein Mouse Annexin A2 (Anxa2)
Protein Synonym Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8
Gene ID 12306
EC No. P07356

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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