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Recombinant Mouse Kininogen-1 (Kng1), N-His
Product Overview
BioVenic's Recombinant Mouse Kininogen-1 (Kng1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 41.0 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Kininogen-1 (Kng1) is a precursor protein that generates biologically active peptides, including bradykinin and kallidin, through the action of proteases like kallikrein. These peptides play crucial roles in regulating blood pressure, inflammation, and pain sensation. Bradykinin, in particular, is a potent vasodilator that increases vascular permeability and promotes the release of nitric oxide and prostaglandins. Kng1 is highly expressed in tissues such as the liver, kidneys, and blood vessels, where it contributes to maintaining cardiovascular homeostasis. Abnormal expression or function of Kng1 has been implicated in various diseases, including hypertension and inflammatory conditions.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.