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Recombinant Guinea Pig Allograft Inflammatory Factor 1 (AIF1), N-His-GST
Product Overview
BioVenic's Recombinant Guinea Pig Allograft Inflammatory Factor 1 (AIF1), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.8 kDa. The purity is> 90%.
Specifications
Target Information
Guinea pig Allograft Inflammatory Factor 1 (AIF1) is a calcium-binding protein that plays a crucial role in intracellular processes such as phagocytosis, membrane ruffling, and F-actin remodeling. It is primarily expressed in macrophages and microglia, and its expression is induced by cytokines like IFN-γ and TNF-α. AIF1 is involved in the activation of macrophages and microglia, contributing to immune responses and inflammation. In the context of transplantation, AIF1 expression correlates with graft rejection and the development of vasculopathy. Additionally, AIF1 has been implicated in various diseases, including kidney disease, rheumatoid arthritis, cancer, cardiovascular diseases, and neurological disorders. Its multifunctional nature makes AIF1 a potential biomarker and therapeutic target for inflammatory and immune-related conditions.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.