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Recombinant Bovine C-C Motif Chemokine (CCL22)
Product Overview
BioVenic's Recombinant Bovine C-C Motif Chemokine (CCL22) is a recombinant protein expressed from E.coli. Its predicted molecular weight is . The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine C-C motif chemokine (CCL22) is a small cytokine that is crucial for the immune system in cattle. It is produced by macrophages and plays a significant role in attracting immune cells such as dendritic cells, NK cells, and specific T cell subsets to sites of inflammation. MDC is particularly effective at attracting CCR4-expressing Th2 and Tc2 cells, suggesting its role in amplifying polarized type II immune responses. It is also implicated in various pathological conditions, from allergic reactions to HIV infection and neoplasia, highlighting its importance in both immune surveillance and disease pathogenesis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.