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Recombinant Bovine C-C Motif Chemokine 8 (CCL8), N-His-GST
Product Overview
BioVenic's Recombinant Bovine C-C Motif Chemokine 8 (CCL8), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.9 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine C-C motif chemokine 8 (CCL8), also known as monocyte chemotactic protein 1 (MCP-1), is a chemokine that plays a significant role in the immune system of cattle. It is a small cytokine that specifically attracts monocytes and other immune cells, such as T cells and dendritic cells, to the sites of inflammation or infection. CCL8 is crucial for the recruitment of leukocytes, particularly during the inflammatory response. It is involved in the pathogenesis of various diseases, either directly or indirectly, such as viral infections, cancers, neuroinflammatory diseases, rheumatoid arthritis, and cardiovascular diseases. The elevated levels of CCL8 have been observed in conditions like COVID-19 in cattle, indicating its importance as a biomarker for disease severity.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.