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Rabbit Anti-Rat Neurocan (NCAN) Polyclonal Antibody

Cat. No.VD3N844

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat neurocan. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat neurocan.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N244
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Neurocan
Isotype IgG
Immunogen Recombinant protein of rat neurocan
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat neurocan (NCAN) is a 136-kDa chondroitin sulfate proteoglycan predominantly expressed in rat central nervous system (CNS) tissues-enriched in brain, spinal cord, and neural progenitor cells. It belongs to the lectican family, contributing to extracellular matrix (ECM) organization in the CNS by interacting with hyaluronan, other proteoglycans, and cell surface receptors. Key functions include regulating neural cell migration, axon guidance, and synaptic plasticity during rat development and adult CNS homeostasis. Dysregulated expression associates with neurodevelopmental disorders, neurodegeneration, and CNS injury. As a critical mediator of CNS ECM structure and neural signaling, rat NCAN is a key target for studying neurobiology, developmental disorders, and neuroprotective therapeutics.

Target Rat Neurocan
Target Synonym CSPG3; NEUR; Neurocan Core Protein; Chondroitin Sulfate Proteoglycan 3; Neurocan Proteoglycan
Gene ID 58982
UniProt ID P55067

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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