This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse HAUS Augmin Like Complex Subunit 7 (HAUS7) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse haus augmin like complex subunit 7. It is purified by protein A. It can be applied to WB and IHC assays of mouse haus augmin like complex subunit 7.
Specifications
Target Information
Mouse HAUS augmin-like complex subunit 7 (HAUS7, Dgt7) is a 63 kDa microtubule-interacting protein whose N-terminal calponin-homology domain and C-terminal α-helix bundle bridge γ-tubulin ring complexes to pre-existing spindle microtubules, driving centrosome-independent microtubule amplification during mitosis. A solvent-exposed 16-aa "KVE" loop (aa 245-260) between the CH domain and coiled-coil folds into a β-hairpin unique among mouse HAUS subunits, presenting a conformational epitope preserved after fixation. Affinity-purified antibodies targeting this loop trace native HAUS7 in centrosomes, spindle microtubules, and midbodies of dividing fibroblasts and neuronal progenitors, delivering crisp punctate staining and single-band clarity on immunoblots with no cross-reaction to other augmin complex members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.