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Mouse Vascular Endothelial Growth Factor B (VEGFB) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Vascular Endothelial Growth Factor B (VEGFB) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse VEGFB in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Vascular Endothelial Growth Factor B (VEGF-B) acts as a growth factor for endothelial cells. VEGF-B167 binds to heparin and neuropilin-1, while the binding of VEGF-B186 to neuropilin-1 is regulated through proteolysis. Although not essential for the development of the cardiovascular system or adult angiogenesis, VEGF-B is important for normal heart function in adults. Mice lacking VEGF-B exhibit smaller hearts, impaired coronary vascular function, and reduced recovery following myocardial ischemia. VEGF-B knockout mice also show accelerated development of insulin resistance and non-alcoholic fatty liver disease (NAFLD). In diabetic mouse models, VEGF-B enhances insulin secretion via the PLCγ and CaMK2 signaling pathways.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.