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Mouse Trypsinogen Activation Peptide (TAP) ELISA Kit-Competitive

Cat. No.EK5F353

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Mouse Trypsinogen Activation Peptide (TAP) ELISA Kit-Competitive is designed for the quantitative determination of Mouse TAP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Mouse Trypsinogen Activation Peptide (TAP).
Target Species Mouse
Species Reactivity Mouse
Detection Range 157-10000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The trypsinogen activation peptide (TAP) is crucial for converting trypsinogen into trypsin, which initiates a cascade of digestive enzyme reactions. In mice, this peptide primarily functions to activate trypsinogen and plays a significant role in pancreatic conditions like acute and chronic pancreatitis. Its regulatory mechanisms include inhibiting self-activation, facilitating external activation, and interacting with other proteases. Following pancreatic injury in mouse models, the concentration of the trypsinogen activation peptide rapidly increases, closely associating with pancreatic cell damage. Researchers can study the peptide's function in these models through gene knockout or chemical induction methods. For instance, T(-/-) mice, which lack the T7 gene, exhibit notably reduced trypsinogen activation and pancreatic damage.

Target/Biomarker Mouse TAP
Target Synonym Trypsinogen Activation Peptide

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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