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Mouse Trypsinogen Activation Peptide (TAP) ELISA Kit-Competitive
Product Overview
BioVenic Mouse Trypsinogen Activation Peptide (TAP) ELISA Kit-Competitive is designed for the quantitative determination of Mouse TAP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.
Specifications
Target Information
The trypsinogen activation peptide (TAP) is crucial for converting trypsinogen into trypsin, which initiates a cascade of digestive enzyme reactions. In mice, this peptide primarily functions to activate trypsinogen and plays a significant role in pancreatic conditions like acute and chronic pancreatitis. Its regulatory mechanisms include inhibiting self-activation, facilitating external activation, and interacting with other proteases. Following pancreatic injury in mouse models, the concentration of the trypsinogen activation peptide rapidly increases, closely associating with pancreatic cell damage. Researchers can study the peptide's function in these models through gene knockout or chemical induction methods. For instance, T(-/-) mice, which lack the T7 gene, exhibit notably reduced trypsinogen activation and pancreatic damage.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.