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Mouse Mucin 2 (MUC2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Mucin 2 (MUC2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MUC2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Mucin-2 serves as a protective and lubricating barrier for the epithelia of the intestines and other organs with mucus membranes, shielding mucosal surfaces from particles and infectious agents. It is a key component of colon mucus, primarily consisting of large polymeric networks formed by MUC2 secreted by goblet cells that cover exposed intestinal surfaces. As a crucial protein in the intestinal mucosal epithelium, Mucin-2 plays a vital role in barrier protection. It safeguards intestinal epithelial cells from external pathogens and harmful substances by forming a mucus layer while preserving the intestinal barrier's integrity. Mice lacking Mucin-2 exhibit pathological characteristics similar to human inflammatory bowel disease (IBD), including elevated expression of Tnf, Il1, and Il7a genes.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.