Mouse Neuropeptide Y Receptor Y2 (NPY2R) ELISA Kit-Sandwich

Neuropeptide Y receptor type 2 (NPY2R) serves as a receptor for neuropeptide Y and peptide YY, playing a multifaceted role in mice. It is involved in regulating energy metabolism, cardiovascular function, neurobehavior, pain response, and various other physiological processes. These functions are mediated by the specific localization of NPY2R in certain cell types, such as neurons and ciliated cells, and its interaction with downstream signaling pathways. In mice, NPY2R is prominently expressed in the hypothalamus, where it is closely associated with energy metabolism and body weight regulation. Research has demonstrated that mice lacking NPY2R exhibit increased appetite, weight gain, and elevated fat deposition, highlighting its critical role in metabolic balance.