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Mouse Tissue Inhibitors of Metalloproteinase 3 (TIMP3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Tissue Inhibitors of Metalloproteinase 3 (TIMP3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TIMP3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Metalloproteinase inhibitor 3 (TIMP-3) forms complexes with metalloproteinases, such as collagenases, and irreversibly deactivates them by binding to their catalytic zinc cofactor. It may be part of a tissue-specific acute response to remodeling stimuli. In mice, TIMP-3 functions in various areas, primarily regulating inflammation, immune response, tissue remodeling, and metabolic diseases. During embryo implantation, TIMP-3, as a key inhibitor of metalloproteinases, balances embryonic invasion and maternal endometrial remodeling by inhibiting MMP-9 activity. TIMP-3 also plays a crucial role in repairing lung injury; its absence can lead to increased degradation of the extracellular matrix (ECM) in alveolar epithelial cells, resulting in lung dysfunction.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.