This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Synaptopodin 2 (SYNPO2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Synaptopodin 2 (SYNPO2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SYNPO2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Synaptopodin-2 exhibits actin-binding and actin-bundling activities, inducing the formation of F-actin networks. At the sarcomeric Z lines, it is thought to function as an adapter protein, linking nascent myofibers to the sarcolemma via ZYX, and may play a role in the early assembly and stabilization of Z lines. In mice, synaptopodin-2 has several important functions, including the regulation of synaptic plasticity, maintenance of glomerular podocyte function, involvement in cancer development, and roles in neurons and muscle tissue. It regulates calcium release by forming clusters and participates in synaptic plasticity. Mice lacking synaptopodin-2 display defects in long-term potentiation (LTP), spatial memory impairment, and impaired synaptic plasticity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Papazoglou, Anna et al. "Sex- and region-specific cortical and hippocampal whole genome transcriptome profiles from control and APP/PS1 Alzheimer's disease mice." PloS one vol. 19,2 e0296959. 7 Feb. 2024.