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Mouse Substance P (SP) ELISA Kit-Sandwich

Cat. No.EK5F297

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Substance P (SP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Substance P (SP).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Substance P is a neuropeptide that exerts its effects by binding to the neurokinin 1 receptor (NK1R). Research indicates that at low doses, substance P can provide analgesic effects by releasing endogenous opioids, whereas high doses may lead to hyperalgesia. In mice, the functions of substance P are varied and intricate, encompassing pain perception, inflammatory response, immune regulation, and the modulation of the respiratory and cardiovascular systems. In a colitis model, substance P levels are significantly elevated, correlating with the degree of inflammation. Additionally, substance P contributes to myocardial remodeling and fibrosis by activating myocardial macrophages.

Target/Biomarker Mouse SP
Target Synonym Substance P

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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