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Bovine D-3-Phosphoglycerate Dehydrogenase (PHGDH) ELISA Kit-Sandwich
Product Overview
BioVenic Bovine D-3-Phosphoglycerate Dehydrogenase (PHGDH) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine D-3-Phosphoglycerate Dehydrogenase (PHGDH) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Bovine D-3-Phosphoglycerate Dehydrogenase is encoded by the PHGDH gene in cattle. This enzyme is essential for the phosphorylated pathway of L-serine biosynthesis. It catalyzes the committed step in de novo serine biosynthesis. Inhibition of PHGDH induces alterations in nucleotide metabolism independent of serine utilization. Dysregulation of PHGDH can impact L-serine availability and contribute to various diseases, including cancer and neurological disorders.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Reid, M. A. et al. Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism. Nature communications. 2018, 9: 5442.